Combined Evaluation of HSV Genome and Antibodies in Breast Cancer

Background: Breast cancer develops due to the combination of external and internal risk factors. Also, role viruses is considerable in developing breast cancer. Objectives: This study compared frequency herpes simplex virus types 1 2 (HSV-1 HSV-2) level IgM IgG antibodies against HSV between patients healthy individuals. Methods: Sixty women with 60 (40 fibroadenoma 20 good health) were selected. tissue serum samples taken from all subjects evaluate HSV-1 HSV-2 genome using real-time PCR. levels assessed ELISA technique. Results: The was detected six specimens two (P = 0.143, OR: 3.22, CI95%: 0.623 - 16.66). Three cases one case positive for 0.309, 3.105, 0.314 30.73). antibody three control group 0.298, 2.11, 0.503 8.87). Although higher mean found (4.01 ± 5.91 U/mL) (2.95 3.51 U/mL), there no statistically significant difference them 0.179). antibody, a its (91.22 13.58 (81.58 17.02 groups 0.008). Conclusions: present showed that not directly related carcinogenesis may act as co-factors.